Retinal toxicity in long term hydroxychloroquine treatment.
نویسندگان
چکیده
منابع مشابه
Retinal toxicity in long term hydroxychloroquine treatment.
OBJECTIVE To report clinical experience from patients with rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) who were receiving recommended doses of hydroxychloroquine for more than six years, and were monitored for evidence of hydroxychloroquine related retinopathy every six months. METHODS A prospective (and continuing) evaluation was made of the potential retinal toxicity of...
متن کاملOcular toxicity of hydroxychloroquine.
OBJECTIVES To review the types, incidence, pathogenesis, risk factors, and clinical characteristics of hydroxychloroquine ocular toxicity and current views about its screening and management. DATA SOURCES Literature search of Medline up to May 2005. STUDY SELECTION Key words for the literature search were 'hydroxychloroquine', 'chloroquine', 'ocular', 'toxicity', 'retinopathy', and 'screeni...
متن کاملContinuation of long term treatment with hydroxychloroquine in systemic lupus erythematosus and rheumatoid arthritis.
BACKGROUND Hydroxychloroquine is used for the treatment of rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE). Long term studies have shown a high rate of termination of hydroxychloroquine treatment in patients with RA. Although it has been shown that discontinuation of treatment with hydroxychloroquine is associated with exacerbation of SLE, long term maintenance rates of treatme...
متن کاملMultifocal electroretinographic evaluation of long-term hydroxychloroquine users.
OBJECTIVES To observe the long-term effects of hydroxychloroquine sulfate on retinal electrical activity by multifocal electroretinography (mfERG) and to evaluate the regional variation of retinal dysfunction in subjects with hydroxychloroquine retinopathy. METHODS Multifocal ERG with 103-hexagon stimulation was performed on 19 patients (36 eyes) treated with hydroxychloroquine for systemic l...
متن کاملCardiac toxicity secondary to long term treatment with chloroquine.
Chloroquine is frequently used to treat systemic autoimmune diseases, such as systemic lupus erythematosus (SLE). With long term treatment, associated toxicity is well known, with retinopathy been the most common complication. Other chronic complications include skin disorders (hyperpigmentation), blood dyscrasias, corneal deposits, encephalopathy, neuropathy, myopathy, and impairment of audito...
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ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1996
ISSN: 0003-4967
DOI: 10.1136/ard.55.3.187